Pseudomonas aeruginosa PAO1, PA1085 (flgJ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1085
Name
flgJ
Replicon chromosome
Genomic location 1170942 - 1172144 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_249776.1
GI 15596282
Affymetrix PA1085_flgJ_at
Entrez 878578
GenBank AAG04474.1
INSDC AAG04474.1
NCBI Locus Tag PA1085
protein_id(GenBank) gb|AAG04474.1|AE004539_16|gnl|PseudoCAP|PA1085
TIGR NTL03PA01086
UniParc UPI000012A941
UniProtKB Acc Q9I4P4
UniProtKB ID FLGJ_PSEAE
UniRef100 UniRef100_Q9I4P4
UniRef50 UniRef50_Q9I4P4
UniRef90 UniRef90_Q9I4P4

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellar protein FlgJ
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 7.48
Kyte-Doolittle Hydrophobicity Value -0.555
Molecular Weight (kDa) 43.2
Isoelectric Point (pI) 9.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0273
Category Flagella
Evidence
Host Organism
Notes
Reference 14617143

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 199 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001047 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1085
Search term: flgJ

Human Homologs

References

Peptidoglycan-hydrolyzing activity of the FlgJ protein, essential for flagellar rod formation in Salmonella typhimurium.
Nambu T, Minamino T, Macnab RM, Kutsukake K
J Bacteriol 1999 Mar;181(5):1555-61
PubMed ID: 10049388
L-, P-, and M-ring proteins of the flagellar basal body of Salmonella typhimurium: gene sequences and deduced protein sequences.
Jones CJ, Homma M, Macnab RM
J Bacteriol 1989 Jul;171(7):3890-900
PubMed ID: 2544561
Flagellar hook and hook-associated proteins of Salmonella typhimurium and their relationship to other axial components of the flagellum.
Homma M, DeRosier DJ, Macnab RM
J Mol Biol 1990 Jun 20;213(4):819-32
PubMed ID: 2193164