Pseudomonas aeruginosa PAO1, PA1187

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA1187
Name
Synonym: lcaD
Replicon chromosome
Genomic location 1288737 - 1289876 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249878.1
GI 15596384
Affymetrix PA1187_at
Entrez 879934
GenBank AAG04576.1
INSDC AAG04576.1
NCBI Locus Tag PA1187
protein_id(GenBank) gb|AAG04576.1|AE004549_3|gnl|PseudoCAP|PA1187
TIGR NTL03PA01188
UniParc UPI00000C5297
UniProtKB Acc Q9I4F1
UniProtKB ID Q9I4F1_PSEAE
UniRef100 UniRef100_W0YMB4
UniRef50 UniRef50_D3P1X3
UniRef90 UniRef90_A0A024HE58

Product

Feature Type CDS
Coding Frame 1
Product Name
probable acyl-CoA dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -2.21
Kyte-Doolittle Hydrophobicity Value -0.190
Molecular Weight (kDa) 42.4
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 464 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001145 (755 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1187

Human Homologs

Ensembl 97, assembly GRCh38.p12
acyl-CoA dehydrogenase long chain [Source:HGNC Symbol;Acc:HGNC:88]
E-value: 7.9e-99
Percent Identity: 48.7

References

Molecular cloning and nucleotide sequence of cDNAs encoding the precursors of rat long chain acyl-coenzyme A, short chain acyl-coenzyme A, and isovaleryl-coenzyme A dehydrogenases. Sequence homology of four enzymes of the acyl-CoA dehydrogenase family.
Matsubara Y, Indo Y, Naito E, Ozasa H, Glassberg R, Vockley J, Ikeda Y, Kraus J, Tanaka K
J Biol Chem 1989 Sep 25;264(27):16321-31
PubMed ID: 2777793
Tissue specific and developmental expression of rat long-and medium-chain acyl-CoA dehydrogenases.
Hainline BE, Kahlenbeck DJ, Grant J, Strauss AW
Biochim. Biophys. Acta 1993 Dec;1216(3):460-8
PubMed ID: 8268228