Pseudomonas aeruginosa PAO1, PA1242 (sprP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA1242
Name
sprP
Replicon chromosome
Genomic location 1343453 - 1345225 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
Comment

Cross-References

RefSeq NP_249933.1
GI 15596439
Affymetrix PA1242_at
Entrez 881237
GenBank AAG04631.1
INSDC AAG04631.1
NCBI Locus Tag PA1242
protein_id(GenBank) gb|AAG04631.1|AE004553_8|gnl|PseudoCAP|PA1242
TIGR NTL03PA01243
UniParc UPI00000C52CB
UniProtKB Acc Q9I496
UniProtKB ID Q9I496_PSEAE
UniRef100 UniRef100_Q9I496
UniRef50 UniRef50_Q9I496
UniRef90 UniRef90_Q9I496

Product

Feature Type CDS
Coding Frame 1
Product Name
SprP
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -12.73
Kyte-Doolittle Hydrophobicity Value -0.365
Molecular Weight (kDa) 64.9
Isoelectric Point (pI) 5.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 17 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001194 (378 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1242
Search term: sprP
Search term: SprP

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Subtilase SprP exerts pleiotropic effects in Pseudomonas aeruginosa.
Pelzer A, Polen T, Funken H, Rosenau F, Wilhelm S, Bott M, Jaeger KE
Microbiologyopen 2014 Feb;3(1):89-103
PubMed ID: 24376018
Functional expression, purification, and biochemical properties of subtilase SprP from Pseudomonas aeruginosa.
Pelzer A, Schwarz C, Knapp A, Wirtz A, Wilhelm S, Smits S, Schmitt L, Funken H, Jaeger KE
Microbiologyopen 2015 Oct;4(5):743-52
PubMed ID: 26175208