Pseudomonas aeruginosa PAO1, PA1245 (aprX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA1245
Name
aprX
Synonym: aprX
Replicon chromosome
Genomic location 1349416 - 1350660 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249936.1
GI 15596442
Affymetrix PA1245_at
Entrez 881251
GenBank AAG04634.1
INSDC AAG04634.1
NCBI Locus Tag PA1245
protein_id(GenBank) gb|AAG04634.1|AE004554_2|gnl|PseudoCAP|PA1245
TIGR NTL03PA01246
UniParc UPI00000CA932
UniProtKB Acc G3XCU0
UniProtKB ID G3XCU0_PSEAE
UniRef100 UniRef100_W0YMG6
UniRef50 UniRef50_A0A077JSQ9
UniRef90 UniRef90_A0A077JSQ9

Product

Feature Type CDS
Coding Frame 1
Product Name
AprX
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -27.35
Kyte-Doolittle Hydrophobicity Value 0.370
Molecular Weight (kDa) 41.4
Isoelectric Point (pI) 4.11

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Extracellular Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in one genus

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001197 (302 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1245
Search term: aprX
Search term: AprX

References

Sequence of a cluster of genes controlling synthesis and secretion of alkaline protease in Pseudomonas aeruginosa: relationships to other secretory pathways.
Duong F, Lazdunski A, Cami B, Murgier M
Gene 1992 Nov 2;121(1):47-54
PubMed ID: 1427098
The AprX protein of Pseudomonas aeruginosa: a new substrate for the Apr type I secretion system.
Duong F, Bonnet E, Géli V, Lazdunski A, Murgier M, Filloux A
Gene 2001 Jan;262(1-2):147-53
PubMed ID: 11179678