Pseudomonas aeruginosa PAO1, PA1278 (cobP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA1278
Name
cobP
Synonym: cobU
Replicon chromosome
Genomic location 1389707 - 1390228 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_249969.1
GI 15596475
Affymetrix PA1278_cobP_at
Entrez 881443
GenBank AAG04667.1
INSDC AAG04667.1
NCBI Locus Tag PA1278
protein_id(GenBank) gb|AAG04667.1|AE004557_8|gnl|PseudoCAP|PA1278
TIGR NTL03PA01279
UniParc UPI00000C52E6
UniProtKB Acc Q9I466
UniProtKB ID COBP_PSEAE
UniRef100 UniRef100_Q9I466
UniRef50 UniRef50_Q9I466
UniRef90 UniRef90_Q9I466

Product

Feature Type CDS
Coding Frame 1
Product Name
cobinamide kinase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.43
Kyte-Doolittle Hydrophobicity Value -0.061
Molecular Weight (kDa) 18.9
Isoelectric Point (pI) 5.36

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 329 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001225 (548 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1278
Search term: cobP
Search term: cobinamide kinase

References

A bifunctional protein from Pseudomonas denitrificans carries cobinamide kinase and cobinamide phosphate guanylyltransferase activities.
Blanche F, Debussche L, Famechon A, Thibaut D, Cameron B, Crouzet J
J Bacteriol 1991 Oct;173(19):6052-7
PubMed ID: 1655696