Pseudomonas aeruginosa PAO1, PA1301 (hxuR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1301
Name
hxuR
Replicon chromosome
Genomic location 1410473 - 1411456 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249992.1
GI 15596498
Affymetrix PA1301_at
DNASU PaCD00006599
Entrez 881570
GenBank AAG04690.1
INSDC AAG04690.1
NCBI Locus Tag PA1301
protein_id(GenBank) gb|AAG04690.1|AE004559_9|gnl|PseudoCAP|PA1301
TIGR NTL03PA01302
UniParc UPI00000C52FC
UniProtKB Acc Q9I443
UniProtKB ID Q9I443_PSEAE
UniRef100 UniRef100_K1CVE0
UniRef50 UniRef50_B7UW19
UniRef90 UniRef90_B7UW19

Product

Feature Type CDS
Coding Frame 1
Product Name
HxuR
Product Name Confidence: Class 1
Synonyms anti-sigma factor HxuR
Evidence for Translation
Charge (pH 7) -0.60
Kyte-Doolittle Hydrophobicity Value -0.240
Molecular Weight (kDa) 36.6
Isoelectric Point (pI) 6.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 139 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001244 (379 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1301
Search term: hxuR
Search term: HxuR

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Pseudomonas aeruginosa possesses three distinct systems for sensing and using the host molecule haem.
Otero-Asman JR, García-García AI, Civantos C, Quesada JM, Llamas MA
Environ Microbiol 2019 Dec;21(12):4629-4647
PubMed ID: 31390127