Pseudomonas aeruginosa PAO1, PA1303

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA1303
Name
Replicon chromosome
Genomic location 1414147 - 1414686 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249994.1
GI 15596500
Affymetrix PA1303_at
Entrez 881561
GenBank AAG04692.1
INSDC AAG04692.1
NCBI Locus Tag PA1303
protein_id(GenBank) gb|AAG04692.1|AE004559_11|gnl|PseudoCAP|PA1303
TIGR NTL03PA01304
UniParc UPI00000C52FE
UniProtKB Acc Q9I441
UniProtKB ID Q9I441_PSEAE
UniRef100 UniRef100_Q9I441
UniRef50 UniRef50_Q9I441
UniRef90 UniRef90_Q9I441

Product

Feature Type CDS
Coding Frame 1
Product Name
signal peptidase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 5.98
Kyte-Doolittle Hydrophobicity Value -0.175
Molecular Weight (kDa) 20.1
Isoelectric Point (pI) 10.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 1
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 556 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001246 (305 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1303
Search term: signal peptidase

References

A novel host-responsive sensor mediates virulence and type III secretion during Pseudomonas aeruginosa-host cell interactions.
O'Callaghan J, Reen FJ, Adams C, Casey PG, Gahan CG, O'Gara F
Microbiology (Reading, Engl.) 2012 Apr;158(Pt 4):1057-70
PubMed ID: 22262100
Pseudomonas aeruginosa possesses two putative type I signal peptidases, LepB and PA1303, each with distinct roles in physiology and virulence.
Waite RD, Rose RS, Rangarajan M, Aduse-Opoku J, Hashim A, Curtis MA
J. Bacteriol. 2012 Sep;194(17):4521-36
PubMed ID: 22730125