Pseudomonas aeruginosa PAO1, PA1326 (ilvA2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA1326
Name
ilvA2
Replicon chromosome
Genomic location 1437067 - 1438614 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250017.1
GI 15596523
Affymetrix PA1326_ilvA2_at
Entrez 878607
GenBank AAG04715.1
INSDC AAG04715.1
NCBI Locus Tag PA1326
protein_id(GenBank) gb|AAG04715.1|AE004562_2|gnl|PseudoCAP|PA1326
TIGR NTL03PA01327
UniParc UPI00000C5315
UniProtKB Acc Q9I418
UniProtKB ID Q9I418_PSEAE
UniRef100 UniRef100_Q9I418
UniRef50 UniRef50_Q9I418
UniRef90 UniRef90_Q9I418

Product

Feature Type CDS
Coding Frame 1
Product Name
threonine dehydratase, biosynthetic
Product Name Confidence: Class 2
Synonyms threonine deaminase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.28
Kyte-Doolittle Hydrophobicity Value -0.070
Molecular Weight (kDa) 55.9
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 618 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000323 (865 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1326
Search term: ilvA2

Human Homologs

Ensembl 97, assembly GRCh38.p12
serine racemase [Source:HGNC Symbol;Acc:HGNC:14398]
E-value: 1.5e-36
Percent Identity: 32.8

References

The complete nucleotide sequence of the ilvGMEDA cluster of Escherichia coli K-12.
Cox JL, Cox BJ, Fidanza V, Calhoun DH
Gene 1987;56(2-3):185-98
PubMed ID: 3315862