Pseudomonas aeruginosa PAO1, PA1436

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1436
Name
Replicon chromosome
Genomic location 1563967 - 1567077 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq NP_250127.1
GI 15596633
Affymetrix PA1436_at
Entrez 881815
GenBank AAG04825.1
INSDC AAG04825.1
NCBI Locus Tag PA1436
protein_id(GenBank) gb|AAG04825.1|AE004573_4|gnl|PseudoCAP|PA1436
TIGR NTL03PA01437
UniParc UPI00000C537E
UniProtKB Acc Q9I3R1
UniProtKB ID Q9I3R1_PSEAE
UniRef100 UniRef100_S0I9G1
UniRef50 UniRef50_A0A085UAG0
UniRef90 UniRef90_B7UWB6

Product

Feature Type CDS
Coding Frame 1
Product Name
probable Resistance-Nodulation-Cell Division (RND) efflux transporter
Product Name Confidence: Class 3
Synonyms probable RND efflux transporter
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.38
Kyte-Doolittle Hydrophobicity Value 0.445
Molecular Weight (kDa) 110.8
Isoelectric Point (pI) 5.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
mexN MexN is the inner membrane transporter of the MexMN-OprM multidrug efflux complex. [PMID:19713238] ARO:3003705 protein homolog model Strict 1915.2 99.9 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001353 (1523 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1436

Human Homologs

References

No references are associated with this feature.