Pseudomonas aeruginosa PAO1, PA1453 (flhF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1453
Name
flhF
Replicon chromosome
Genomic location 1582528 - 1583817 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250144.1
GI 15596650
Affymetrix PA1453_flhF_at
Entrez 881865
GenBank AAG04842.1
INSDC AAG04842.1
NCBI Locus Tag PA1453
protein_id(GenBank) gb|AAG04842.1|AE004575_1|gnl|PseudoCAP|PA1453
TIGR NTL03PA01454
UniParc UPI00000C538B
UniProtKB Acc Q9I3P8
UniProtKB ID FLHF_PSEAE
UniRef100 UniRef100_Q9I3P8
UniRef50 UniRef50_Q9I3P8
UniRef90 UniRef90_Q9I3P8

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellar biosynthesis protein FlhF
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 10.15
Kyte-Doolittle Hydrophobicity Value -0.185
Molecular Weight (kDa) 46.5
Isoelectric Point (pI) 9.98

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0273
Category Flagella
Evidence
Host Organism
Notes
Reference 14617143

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 595 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001368 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1453
Search term: flhF

Human Homologs

References

flhF, a Bacillus subtilis flagellar gene that encodes a putative GTP-binding protein.
Carpenter PB, Hanlon DW, Ordal GW
Mol Microbiol 1992 Sep;6(18):2705-13
PubMed ID: 1447978
Identification of a chemotaxis gene region from Pseudomonas putida.
Ditty JL, Grimm AC, Harwood CS
FEMS Microbiol Lett 1998 Feb 15;159(2):267-73
PubMed ID: 9503621