Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1454
|
Name |
fleN
Synonym: motR |
Replicon | chromosome |
Genomic location | 1583956 - 1584798 (+ strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_250145.1 |
GI | 15596651 |
Affymetrix | PA1454_at |
Entrez | 881866 |
GenBank | AAG04843.1 |
INSDC | AAG04843.1 |
NCBI Locus Tag | PA1454 |
protein_id(GenBank) | gb|AAG04843.1|AE004575_2|gnl|PseudoCAP|PA1454 |
TIGR | NTL03PA01455 |
UniParc | UPI00000D426B |
UniProtKB Acc | G3XD64 |
UniProtKB ID | G3XD64_PSEAE |
UniRef100 | UniRef100_G3XD64 |
UniRef50 | UniRef50_G3XD64 |
UniRef90 | UniRef90_G3XD64 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
flagellar synthesis regulator FleN
|
Synonyms |
MotR |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 3.62 |
Kyte-Doolittle Hydrophobicity Value | 0.196 |
Molecular Weight (kDa) | 30.0 |
Isoelectric Point (pI) | 8.70 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
7EJW | TRANSCRIPTION | 04/02/21 | Crystal structure of FleN in complex with FleQ AAA+ doamain | Pseudomonas aeruginosa PAO1 | 1.98 | X-RAY DIFFRACTION | 100.0 |
5JVF | TRANSCRIPTION | 05/11/16 | Crystal Structure of Apo-FleN | Pseudomonas aeruginosa PAO1 | 1.66 | X-RAY DIFFRACTION | 100.0 |
5J1J | TRANSCRIPTION | 03/29/16 | Structure of FleN-AMPPNP complex | Pseudomonas aeruginosa PAO1 | 1.55 | X-RAY DIFFRACTION | 100.0 |
Source 1 | |
Database | VFDB : VF0273 |
Category | Flagella |
Evidence |
|
Host Organism | |
Notes | |
Reference | 14617143 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 637 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001369 (535 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1454
Search term: fleN
Search term: flagellar synthesis regulator FleN
|
Ensembl
110, assembly
GRCh38.p14
|
NUBP iron-sulfur cluster assembly factor 2, cytosolic [Source:HGNC Symbol;Acc:HGNC:8042]
E-value:
5.9e-10
Percent Identity:
26.6
|
Activation of the multiple drug resistance gene MDR1 in fluconazole-resistant, clinical Candida albicans strains is caused by mutations in a trans-regulatory factor.
Wirsching S, Michel S, Köhler G, Morschhäuser J
J Bacteriol 2000 Jan;182(2):400-4
PubMed ID: 10629186
|
The pseudomonas aeruginosa motR gene involved in regulation of bacterial motility.
Campos-García J, Nájera R, Camarena L, Soberón-Chávez G
FEMS Microbiol Lett 2000 Mar 1;184(1):57-62
PubMed ID: 10689166
|
A putative ATP-binding protein from the che/fla locus of Bacillus subtilis.
Kirsch ML, Carpenter PB, Ordal GW
DNA Seq 1994;4(4):271-5
PubMed ID: 7987014
|
The Pseudomonas aeruginosa rhlG gene encodes an NADPH-dependent beta-ketoacyl reductase which is specifically involved in rhamnolipid synthesis.
Campos-García J, Caro AD, Nájera R, Miller-Maier RM, Al-Tahhan RA, Soberón-Chávez G
J Bacteriol 1998 Sep;180(17):4442-51
PubMed ID: 9721281
|