Pseudomonas aeruginosa PAO1, PA1466

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1466
Name
Replicon chromosome
Genomic location 1595032 - 1595718 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250157.1
GI 15596663
Affymetrix PA1466_at
DNASU PaCD00006674
Entrez 881541
GenBank AAG04855.1
INSDC AAG04855.1
NCBI Locus Tag PA1466
protein_id(GenBank) gb|AAG04855.1|AE004576_4|gnl|PseudoCAP|PA1466
TIGR NTL03PA01467
UniParc UPI00000C538D
UniProtKB Acc Q9I3P6
UniProtKB ID Q9I3P6_PSEAE
UniRef100 UniRef100_Q9I3P6
UniRef50 UniRef50_A0A022P346
UniRef90 UniRef90_A0A022P346

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.23
Kyte-Doolittle Hydrophobicity Value -0.201
Molecular Weight (kDa) 25.5
Isoelectric Point (pI) 6.31

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 124 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001381 (337 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1466

Human Homologs

References

The amino acid sequence of glutathione transferase from Proteus mirabilis, a prototype of a new class of enzymes.
Mignogna G, Allocati N, Aceto A, Piccolomini R, Di Ilio C, Barra D, Martini F
Eur J Biochem 1993 Feb 1;211(3):421-5
PubMed ID: 8436105
Molecular cloning and site-directed mutagenesis of glutathione S-transferase from Escherichia coli. The conserved tyrosyl residue near the N terminus is not essential for catalysis.
Nishida M, Kong KH, Inoue H, Takahashi K
J Biol Chem 1994 Dec 23;269(51):32536-41
PubMed ID: 7798255