Pseudomonas aeruginosa PAO1, PA1475 (ccmA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1475
Name
ccmA
Synonym: cycV
Synonym: helA
Replicon chromosome
Genomic location 1602179 - 1602880 (+ strand)

Cross-References

RefSeq NP_250166.1
GI 15596672
Affymetrix PA1475_ccmA_at
DNASU PaCD00006679
Entrez 880978
GenBank AAG04864.1
INSDC AAG04864.1
NCBI Locus Tag PA1475
protein_id(GenBank) gb|AAG04864.1|AE004576_13|gnl|PseudoCAP|PA1475
TIGR NTL03PA01476
UniParc UPI00000C5396
UniProtKB Acc Q9I3N7
UniProtKB ID CCMA_PSEAE
UniRef100 UniRef100_Q9I3N7
UniRef50 UniRef50_Q48GL0
UniRef90 UniRef90_Q9I3N7

Product

Feature Type CDS
Coding Frame 1
Product Name
heme exporter protein CcmA
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.44
Kyte-Doolittle Hydrophobicity Value -0.009
Molecular Weight (kDa) 25.0
Isoelectric Point (pI) 5.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001390 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1475
Search term: ccmA

Human Homologs

Ensembl 94, assembly GRCh38.p12
ATP binding cassette subfamily A member 6 [Source:HGNC Symbol;Acc:HGNC:36]
E-value: 1.3e-14
Percent Identity: 31.8

References

Escherichia coli genes required for cytochrome c maturation.
Thöny-Meyer L, Fischer F, Künzler P, Ritz D, Hennecke H
J. Bacteriol. 1995 Aug;177(15):4321-6
PubMed ID: 7635817