Pseudomonas aeruginosa PAO1, PA1482 (ccmH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA1482
Name
ccmH
Synonym: ccl2
Synonym: cycL
Replicon chromosome
Genomic location 1607604 - 1608071 (+ strand)

Cross-References

RefSeq NP_250173.1
GI 15596679
Affymetrix PA1482_ccmH_at
DNASU PaCD00006684
Entrez 881029
GenBank AAG04871.1
INSDC AAG04871.1
NCBI Locus Tag PA1482
protein_id(GenBank) gb|AAG04871.1|AE004577_6|gnl|PseudoCAP|PA1482
TIGR NTL03PA01483
UniParc UPI00000C539C
UniProtKB Acc Q9I3N0
UniProtKB ID CCMH_PSEAE
UniRef100 UniRef100_Q9I3N0
UniRef50 UniRef50_P52226
UniRef90 UniRef90_Q9I3N0

Product

Feature Type CDS
Coding Frame 1
Product Name
cytochrome C-type biogenesis protein CcmH
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 5.90
Kyte-Doolittle Hydrophobicity Value -0.176
Molecular Weight (kDa) 17.4
Isoelectric Point (pI) 9.75

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2HL7 OXIDOREDUCTASE 07/06/06 Crystal structure of the periplasmic domain of CcmH from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 1.7 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 187 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001397 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1482
Search term: ccmH

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Transcriptional control and essential roles of the Escherichia coli ccm gene products in formate-dependent nitrite reduction and cytochrome c synthesis.
Tanapongpipat S, Reid E, Cole JA, Crooke H
Biochem. J. 1998 Sep;334 ( Pt 2)
PubMed ID: 9716493