Pseudomonas aeruginosa PAO1, PA1486 (bapF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1486
Name
bapF
Replicon chromosome
Genomic location 1612126 - 1613226 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250177.1
GI 15596683
Affymetrix PA1486_at
Entrez 881720
GenBank AAG04875.1
INSDC AAG04875.1
NCBI Locus Tag PA1486
protein_id(GenBank) gb|AAG04875.1|AE004577_10|gnl|PseudoCAP|PA1486
TIGR NTL03PA01487
UniParc UPI00000C53A0
UniProtKB Acc Q9I3M6
UniProtKB ID Q9I3M6_PSEAE
UniRef100 UniRef100_Q9I3M6
UniRef50 UniRef50_Q9I3M6
UniRef90 UniRef90_Q9I3M6

Product

Feature Type CDS
Coding Frame 1
Product Name
beta-peptidyl aminopeptidase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -5.25
Kyte-Doolittle Hydrophobicity Value -0.125
Molecular Weight (kDa) 38.5
Isoelectric Point (pI) 5.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 130 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001400 (389 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1486
Search term: bapF

Human Homologs

References

Mutation of active site serine residue with cysteine displays change in acyl-acceptor preference of β-peptidyl aminopeptidase from Pseudomonas aeruginosa PAO1.
Arima J, Tanaka A, Morimoto M, Mori N
Appl. Microbiol. Biotechnol. 2014 Feb;98(4):1631-40
PubMed ID: 23728237