Pseudomonas aeruginosa PAO1, PA3290 (tle1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3290
Name
tle1
Replicon chromosome
Genomic location 3681500 - 3684148 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 10 transposon mutants in orthologs

Cross-References

RefSeq NP_251980.1
GI 15598486
Affymetrix PA3290_at
Entrez 882453
GenBank AAG06678.1
NCBI Locus Tag PA3290
protein_id(GenBank) gb|AAG06678.1|AE004751_4|gnl|PseudoCAP|PA3290
TIGR NTL03PA03290
UniProtKB Acc Q9HYV3
UniProtKB ID Q9HYV3_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
Tle1
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -13.88
Kyte-Doolittle Hydrophobicity Value -0.287
Molecular Weight (kDa) 96.5
Isoelectric Point (pI) 5.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4O5P HYDROLASE 12/19/13 Crystal structure of an uncharacterized protein from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.001 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 28 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000090 (3342 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3290
Search term: tle1
Search term: Tle1

Human Homologs

References

Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors.
Russell AB, LeRoux M, Hathazi K, Agnello DM, Ishikawa T, Wiggins PA, Wai SN, Mougous JD
Nature 2013 Apr 25;496(7446):508-12
PubMed ID: 23552891