Pseudomonas aeruginosa PAO1, PA3294 (vgrG4a)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3294
Name
vgrG4a
Replicon chromosome
Genomic location 3686584 - 3688650 (- strand)
Transposon Mutants 7 transposon mutants in PAO1
Transposon Mutants in orthologs 10 transposon mutants in orthologs

Cross-References

RefSeq NP_251984.1
GI 15598490
Affymetrix PA3294_s_at
Entrez 882457
GenBank AAG06682.1
INSDC AAG06682.1
NCBI Locus Tag PA3294
protein_id(GenBank) gb|AAG06682.1|AE004751_8|gnl|PseudoCAP|PA3294
TIGR NTL03PA03294
UniParc UPI00000C5999
UniProtKB Acc Q9HYU9
UniProtKB ID Q9HYU9_PSEAE
UniRef100 UniRef100_Q9HYU9
UniRef50 UniRef50_Q9HYC3
UniRef90 UniRef90_Q9HYC3

Product

Feature Type CDS
Coding Frame 1
Product Name
VgrG4a
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -12.23
Kyte-Doolittle Hydrophobicity Value -0.526
Molecular Weight (kDa) 77.0
Isoelectric Point (pI) 6.34

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 142 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000090 (3342 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3294
Search term: vgrG4a
Search term: VgrG4a

Human Homologs

References

Rhs elements comprise three subfamilies which diverged prior to acquisition by Escherichia coli.
Wang YD, Zhao S, Hill CW
J Bacteriol 1998 Aug;180(16):4102-10
PubMed ID: 9696756
Type VI secretion system in Pseudomonas aeruginosa: secretion and multimerization of VgrG proteins.
Hachani A, Lossi NS, Hamilton A, Jones C, Bleves S, Albesa-Jové D, Filloux A
J Biol Chem 2011 Apr 8;286(14):12317-27
PubMed ID: 21325275