Pseudomonas aeruginosa PAO1, PA4462 (rpoN)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA4462
Name
rpoN
Synonym: ntrA
Replicon chromosome
Genomic location 4992870 - 4994363 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253152.1
GI 15599658
Affymetrix PA4462_rpoN_at
Entrez 881022
GenBank AAG07850.1
INSDC AAG07850.1
NCBI Locus Tag PA4462
protein_id(GenBank) gb|AAG07850.1|AE004860_6|gnl|PseudoCAP|PA4462
TIGR NTL03PA04463
UniParc UPI000013457A
UniProtKB Acc P49988
UniProtKB ID RP54_PSEAE
UniRef100 UniRef100_P49988
UniRef50 UniRef50_P0A171
UniRef90 UniRef90_P49988

Product

Feature Type CDS
Coding Frame 1
Product Name
RNA polymerase sigma-54 factor
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -29.12
Kyte-Doolittle Hydrophobicity Value -0.438
Molecular Weight (kDa) 56.1
Isoelectric Point (pI) 4.43

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 397 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004051 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4462
Search term: rpoN

References

Nucleotide sequence of the rpoN gene and characterization of two downstream open reading frames in Pseudomonas aeruginosa.
Jin S, Ishimoto K, Lory S
J. Bacteriol. 1994 Mar;176(5):1316-22
PubMed ID: 8113171
The Pseudomonas aeruginosa sensor kinase KinB negatively controls alginate production through AlgW-dependent MucA proteolysis.
Damron FH, Qiu D, Yu HD
J. Bacteriol. 2009 Apr;191(7):2285-95
PubMed ID: 19168621