Pseudomonas aeruginosa PAO1, PA4757

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4757
Name
Synonym: yeaS
Replicon chromosome
Genomic location 5343105 - 5343755 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_253445.1
GI 15599951
Affymetrix PA4757_at
DNASU PaCD00008064
Entrez 881750
GenBank AAG08143.1
INSDC AAG08143.1
NCBI Locus Tag PA4757
protein_id(GenBank) gb|AAG08143.1|AE004889_6|gnl|PseudoCAP|PA4757
TIGR NTL03PA04758
UniParc UPI000013A313
UniProtKB Acc P38102
UniProtKB ID Y4757_PSEAE
UniRef100 UniRef100_P38102
UniRef50 UniRef50_P38102
UniRef90 UniRef90_P38102

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 9.19
Kyte-Doolittle Hydrophobicity Value 0.875
Molecular Weight (kDa) 23.2
Isoelectric Point (pI) 10.39

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 317 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002009 (1230 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4757

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295