Pseudomonas aeruginosa PAO1, PA4900

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4900
Name
Replicon chromosome
Genomic location 5497313 - 5498653 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 6 transposon mutants in orthologs
Commenttranscription induced by vanillate

Cross-References

RefSeq NP_253587.1
GI 15600093
Affymetrix PA4900_at
Entrez 882176
GenBank AAG08285.1
INSDC AAG08285.1
NCBI Locus Tag PA4900
protein_id(GenBank) gb|AAG08285.1|AE004903_3|gnl|PseudoCAP|PA4900
TIGR NTL03PA04901
UniParc UPI00000C5E6A
UniProtKB Acc Q9HUR3
UniProtKB ID Q9HUR3_PSEAE
UniRef100 UniRef100_W0YUJ6
UniRef50 UniRef50_T2H5Z5
UniRef90 UniRef90_A0A077K0M1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 10.83
Kyte-Doolittle Hydrophobicity Value 0.731
Molecular Weight (kDa) 46.8
Isoelectric Point (pI) 10.06

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 390 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000234 (2404 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4900

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295