Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA5324
|
Name |
sphR
|
Replicon | chromosome |
Genomic location | 5994741 - 5995811 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Comment | Binds sphingosine and induces expression of sphA (PA5325), sphBCD (PA5328-PA5326), and cerN (PA0845) |
RefSeq | NP_254011.1 |
GI | 15600517 |
Affymetrix | PA5324_at |
Entrez | 879621 |
GenBank | AAG08709.1 |
INSDC | AAG08709.1 |
NCBI Locus Tag | PA5324 |
protein_id(GenBank) | gb|AAG08709.1|AE004945_3|gnl|PseudoCAP|PA5324 |
TIGR | NTL03PA05325 |
UniParc | UPI00000C5FA5 |
UniProtKB Acc | Q9HTN1 |
UniProtKB ID | Q9HTN1_PSEAE |
UniRef100 | UniRef100_W0Z282 |
UniRef50 | UniRef50_Q4KAC5 |
UniRef90 | UniRef90_W0Z282 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Sphingosine-responsive Regulator, SphR
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | 3.77 |
Kyte-Doolittle Hydrophobicity Value | -0.085 |
Molecular Weight (kDa) | 39.8 |
Isoelectric Point (pI) | 8.05 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 228 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000800 (1482 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA5324
Search term: sphR
Search term: Sphingosine-responsive Regulator, SphR
|
Detection of host-derived sphingosine by Pseudomonas aeruginosa is important for survival in the murine lung.
LaBauve AE, Wargo MJ
PLoS Pathog 2014 Jan;10(1):e1003889
PubMed ID: 24465209
|