Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA5418
|
Name |
soxA
|
Replicon | chromosome |
Genomic location | 6097024 - 6100041 (+ strand) |
Transposon Mutants | 5 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | Strains with transposon mutants in any of the soxBDAG genes are unable to grow on choline, glycine betaine, dimethylglcycine or sarcosine. |
Comment | NMR analysis shows buildup of labeled sarcosine when soxA transposon mutants are given labeled choline. |
RefSeq | NP_254105.1 |
GI | 15600611 |
Affymetrix | PA5418_soxA_at |
Entrez | 880824 |
GenBank | AAG08803.1 |
INSDC | AAG08803.1 |
NCBI Locus Tag | PA5418 |
protein_id(GenBank) | gb|AAG08803.1|AE004954_5|gnl|PseudoCAP|PA5418 |
TIGR | NTL03PA05419 |
UniParc | UPI00000C5FF5 |
UniProtKB Acc | Q9HTE6 |
UniProtKB ID | Q9HTE6_PSEAE |
UniRef100 | UniRef100_Q9HTE6 |
UniRef50 | UniRef50_Q9HTE6 |
UniRef90 | UniRef90_Q9HTE6 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
sarcosine oxidase alpha subunit
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | 4.76 |
Kyte-Doolittle Hydrophobicity Value | -0.236 |
Molecular Weight (kDa) | 109.4 |
Isoelectric Point (pI) | 7.53 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 498 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004972 (512 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA5418
Search term: soxA
Search term: sarcosine oxidase alpha subunit
|
Ensembl
110, assembly
GRCh38.p14
|
dimethylglycine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:24475]
E-value:
1.0e-32
Percent Identity:
27.3
|
Sequence analysis of sarcosine oxidase and nearby genes reveals homologies with key enzymes of folate one-carbon metabolism.
Chlumsky LJ, Zhang L, Jorns MS
J Biol Chem 1995 Aug 4;270(31):18252-9
PubMed ID: 7543100
|
Identification of two gene clusters and a transcriptional regulator required for Pseudomonas aeruginosa glycine betaine catabolism.
Wargo MJ, Szwergold BS, Hogan DA
J Bacteriol 2008 Apr;190(8):2690-9
PubMed ID: 17951379
|