Pseudomonas aeruginosa PAO1, PA5419 (soxG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA5419
Name
soxG
Replicon chromosome
Genomic location 6100135 - 6100770 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
CommentStrains with transposon mutants in any of the soxBDAG genes are unable to grow on choline, glycine betaine, dimethylglcycine or sarcosine.

Cross-References

RefSeq NP_254106.1
GI 15600612
Affymetrix PA5419_soxG_at
DNASU PaCD00008341
Entrez 880825
GenBank AAG08804.1
INSDC AAG08804.1
NCBI Locus Tag PA5419
protein_id(GenBank) gb|AAG08804.1|AE004954_6|gnl|PseudoCAP|PA5419
TIGR NTL03PA05420
UniParc UPI00000C5FF6
UniProtKB Acc Q9HTE5
UniProtKB ID Q9HTE5_PSEAE
UniRef100 UniRef100_W0Z1T9
UniRef50 UniRef50_Q4K4Q0
UniRef90 UniRef90_B7V5W0

Product

Feature Type CDS
Coding Frame 1
Product Name
sarcosine oxidase gamma subunit
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -3.87
Kyte-Doolittle Hydrophobicity Value -0.016
Molecular Weight (kDa) 23.0
Isoelectric Point (pI) 6.23

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 61 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004973 (530 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5419
Search term: soxG

References

Sequence analysis of sarcosine oxidase and nearby genes reveals homologies with key enzymes of folate one-carbon metabolism.
Chlumsky LJ, Zhang L, Jorns MS
J. Biol. Chem. 1995 Aug;270(31):18252-9
PubMed ID: 7543100
Identification of two gene clusters and a transcriptional regulator required for Pseudomonas aeruginosa glycine betaine catabolism.
Wargo MJ, Szwergold BS, Hogan DA
J. Bacteriol. 2008 Apr;190(8):2690-9
PubMed ID: 17951379