Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA5427
|
Name |
adhA
|
Replicon | chromosome |
Genomic location | 6107111 - 6108139 (+ strand) |
Transposon Mutants | 5 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_254114.1 |
GI | 15600620 |
Affymetrix | PA5427_adhA_at |
DNASU | PaCD00008344 |
Entrez | 877625 |
GenBank | AAG08812.1 |
INSDC | AAG08812.1 |
NCBI Locus Tag | PA5427 |
protein_id(GenBank) | gb|AAG08812.1|AE004955_6|gnl|PseudoCAP|PA5427 |
TIGR | NTL03PA05428 |
UniParc | UPI00000C5FFC |
UniProtKB Acc | Q9HTD9 |
UniProtKB ID | Q9HTD9_PSEAE |
UniRef100 | UniRef100_W0Z1V1 |
UniRef50 | UniRef50_F9DQT4 |
UniRef90 | UniRef90_W0Z1V1 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
alcohol dehydrogenase
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (35.91 kDa, PMID:21751344)
|
Charge (pH 7) | -6.81 |
Kyte-Doolittle Hydrophobicity Value | 0.165 |
Molecular Weight (kDa) | 35.9 |
Isoelectric Point (pI) | 5.78 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
1LLU | OXIDOREDUCTASE | 04/30/02 | THE TERNARY COMPLEX OF PSEUDOMONAS AERUGINOSA ALCOHOL DEHYDROGENASE WITH ITS COENZYME AND WEAK SUBSTRATE | Pseudomonas aeruginosa | 2.3 | X-RAY DIFFRACTION | 99.4 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 578 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004980 (420 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA5427
Search term: adhA
Search term: alcohol dehydrogenase
|
A few amino acid substitutions are responsible for the higher thermostability of a novel NAD(+)-dependent bacillar alcohol dehydrogenase.
Cannio R, Rossi M, Bartolucci S
Eur J Biochem 1994 Jun 1;222(2):345-52
PubMed ID: 8020473
|
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
|