Pseudomonas aeruginosa PAO1, PA5443 (uvrD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA5443
Name
uvrD
Synonym: rad
Synonym: pdeB
Synonym: mutU
Synonym: recL
Replicon chromosome
Genomic location 6131088 - 6133274 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_254130.1
GI 15600636
Affymetrix PA5443_uvrD_at
Entrez 877766
GenBank AAG08828.1
INSDC AAG08828.1
NCBI Locus Tag PA5443
protein_id(GenBank) gb|AAG08828.1|AE004957_3|gnl|PseudoCAP|PA5443
TIGR NTL03PA05444
UniParc UPI00000C4ECE
UniProtKB Acc G3XD04
UniProtKB ID G3XD04_PSEAE
UniRef100 UniRef100_G3XD04
UniRef50 UniRef50_P03018
UniRef90 UniRef90_G3XD04

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA helicase II
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -13.64
Kyte-Doolittle Hydrophobicity Value -0.283
Molecular Weight (kDa) 81.5
Isoelectric Point (pI) 5.67

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 640 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004994 (551 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5443
Search term: uvrD
Search term: DNA helicase II

References

Determination of the initiation sites of transcription and translation of the uvrD gene of Escherichia coli.
Yamamoto Y, Ogawa T, Shinagawa H, Nakayama T, Matsuo H, Ogawa H
J. Biochem. 1986 Jun;99(6):1579-90
PubMed ID: 2943729
Characterization of DNA helicase II from a uvrD252 mutant of Escherichia coli.
Washburn BK, Kushner SR
J. Bacteriol. 1993 Jan;175(2):341-50
PubMed ID: 8419285