Pseudomonas aeruginosa PAO1, PA5459

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5459
Name
Replicon chromosome
Genomic location 6150315 - 6151151 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_254146.1
GI 15600652
Affymetrix PA5459_at
Entrez 879497
GenBank AAG08844.1
INSDC AAG08844.1
NCBI Locus Tag PA5459
protein_id(GenBank) gb|AAG08844.1|AE004958_14|gnl|PseudoCAP|PA5459
TIGR NTL03PA05460
UniParc UPI00000C6018
UniProtKB Acc Q9HTB1
UniProtKB ID Q9HTB1_PSEAE
UniRef100 UniRef100_Q9HTB1
UniRef50 UniRef50_Q9HTB1
UniRef90 UniRef90_Q9HTB1

Product

Feature Type CDS
Coding Frame 1
Product Name
putative methyltransferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -12.43
Kyte-Doolittle Hydrophobicity Value -0.082
Molecular Weight (kDa) 30.7
Isoelectric Point (pI) 4.67

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 220 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000771 (1346 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5459

Human Homologs

References

Five new genes are important for common polysaccharide antigen biosynthesis in Pseudomonas aeruginosa.
Hao Y, King JD, Huszczynski S, Kocíncová D, Lam JS
mBio 2013 Jan 22;4(1):e00631-12
PubMed ID: 23341552