Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA5514
|
Name |
|
Replicon | chromosome |
Genomic location | 6207241 - 6208029 (+ strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_254201.1 |
GI | 15600707 |
Affymetrix | PA5514_at |
Entrez | 877990 |
GenBank | AAG08899.1 |
INSDC | AAG08899.1 |
NCBI Locus Tag | PA5514 |
protein_id(GenBank) | gb|AAG08899.1|AE004964_2|gnl|PseudoCAP|PA5514 |
TIGR | NTL03PA05515 |
UniParc | UPI00000C6049 |
UniProtKB Acc | G3XCV9 |
UniProtKB ID | G3XCV9_PSEAE |
UniRef100 | UniRef100_Q6PLK5 |
UniRef50 | UniRef50_Q6JTT6 |
UniRef90 | UniRef90_Q6JTT6 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
probable beta-lactamase
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | 5.90 |
Kyte-Doolittle Hydrophobicity Value | -0.185 |
Molecular Weight (kDa) | 29.1 |
Isoelectric Point (pI) | 9.57 |
Individual Mappings | |
Additional evidence for subcellular localization |
Identified using the Resistance Gene Identifier (RGI)
Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
OXA-50 | OXA-50 is a beta-lactamase found in Pseudomonas aeruginosa. It confers decreased susceptibility to ampicillin and ticarcillin and, interestingly, to moxalactam and meropenem in P. aeruginosa but not in E. coli. Also confers resistance to piperacillin-tazobactam and cephalotin. [PMID:15155197] | ARO:3001796 | protein homolog model | Perfect | 542.0 | 100.0 | 3.2.5 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 90 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG005052 (303 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA5514
Search term: probable beta-lactamase
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Phylogeny of LCR-1 and OXA-5 with class A and class D beta-lactamases.
Couture F, Lachapelle J, Levesque RC
Mol Microbiol 1992 Jun;6(12):1693-705
PubMed ID: 1495394
|