Pseudomonas aeruginosa PAO1, PA5539

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA5539
Name
Replicon chromosome
Genomic location 6231662 - 6232558 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
CommentDeaminates 2-aminoacrylate in vitro

Cross-References

RefSeq NP_254226.1
GI 15600732
Affymetrix PA5539_at
DNASU PaCD00008385
Entrez 877616
GenBank AAG08924.1
INSDC AAG08924.1
NCBI Locus Tag PA5539
protein_id(GenBank) gb|AAG08924.1|AE004966_6|gnl|PseudoCAP|PA5539
TIGR NTL03PA05540
UniParc UPI00000C6061
UniProtKB Acc Q9HT35
UniProtKB ID GCH4_PSEAE
UniRef100 UniRef100_B7V776
UniRef50 UniRef50_Q4K3E8
UniRef90 UniRef90_B7V776

Product

Feature Type CDS
Coding Frame 1
Product Name
RidA subfamily protein
Product Name Confidence: Class 1
Synonyms 2-aminoacrylate deaminase
Evidence for Translation
Charge (pH 7) -5.50
Kyte-Doolittle Hydrophobicity Value -0.067
Molecular Weight (kDa) 32.4
Isoelectric Point (pI) 6.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 113 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005072 (518 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5539

References

Members of the Rid protein family have broad imine deaminase activity and can accelerate the Pseudomonas aeruginosa D-arginine dehydrogenase (DauA) reaction in vitro.
Hodge-Hanson KM, Downs DM
PLoS One 2017;12(9):e0185544
PubMed ID: 28957411
PA5339, a RidA Homolog, Is Required for Full Growth in Pseudomonas aeruginosa.
Irons J, Hodge-Hanson KM, Downs DM
J Bacteriol 2018 Nov 15;200(22)
PubMed ID: 30181125