Pseudomonas putida BIRD-1, PPUBIRD1_4181

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas putida BIRD-1
GCF_000183645.1|latest
Locus Tag
PPUBIRD1_4181
Name
Replicon chromosome
Genomic location 4670054 - 4671406 (- strand)

Cross-References

RefSeq YP_005931965.1
GI 386013688
EC Number 5.5.1.2
Entrez 12522359
NCBI Locus Tag PPUBIRD1_4181

Product

Feature Type CDS
Coding Frame 1
Product Name
3-carboxy-cis,cis-muconate cycloisomerase
Synonyms
Evidence for Translation
Charge (pH 7) -3.77
Kyte-Doolittle Hydrophobicity Value 0.034
Molecular Weight (kDa) 48.2
Isoelectric Point (pI) 6.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1RE5 ISOMERASE 11/06/03 Crystal structure of 3-carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida Pseudomonas putida 2.6 X-RAY DIFFRACTION 99.6

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
Citric acid DB04272 DrugBank 5.1.4 P32427 3-carboxy-cis,cis-muconate cycloisomerase 95.3 422 3.8e-221
1,4-Dithiothreitol DB04447 DrugBank 5.1.4 P32427 3-carboxy-cis,cis-muconate cycloisomerase 95.3 422 3.8e-221

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 647 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000229 (504 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PPUBIRD1_4181

Human Homologs

References

No references are associated with this feature.