Pseudomonas putida BIRD-1, PPUBIRD1_4183

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas putida BIRD-1
GCF_000183645.1|latest
Locus Tag
PPUBIRD1_4183
Name
Replicon chromosome
Genomic location 4672893 - 4674095 (- strand)

Cross-References

RefSeq YP_005931967.1
GI 386013690
EC Number 2.3.1.174
Entrez 12522361
NCBI Locus Tag PPUBIRD1_4183

Product

Feature Type CDS
Coding Frame 1
Product Name
beta-ketoadipyl-CoA thiolase
Synonyms
Evidence for Translation
Charge (pH 7) -3.66
Kyte-Doolittle Hydrophobicity Value 0.082
Molecular Weight (kDa) 41.9
Isoelectric Point (pI) 6.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6PCD TRANSFERASE 06/17/19 Crystal structure of beta-ketoadipyl-CoA thiolase mutant (C90S-H356A) in complex Octanoyl coenzyme A Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440) 1.37 X-RAY DIFFRACTION 99.0
6PCA TRANSFERASE 06/17/19 Crystal structure of beta-ketoadipyl-CoA thiolase Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440) 1.81 X-RAY DIFFRACTION 99.5
6PCB TRANSFERASE 06/17/19 Crystal structure of beta-ketoadipyl-CoA thiolase mutant (H356A) in complex with COA Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440) 1.61 X-RAY DIFFRACTION 99.2
6PCC TRANSFERASE 06/17/19 Crystal structure of beta-ketoadipyl-CoA thiolase mutant (H356A) in complex hexanoyl coenzyme A Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440) 1.96 X-RAY DIFFRACTION 99.2

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 479 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000227 (529 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PPUBIRD1_4183

Human Homologs

Ensembl 110, assembly GRCh38.p14
acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83]
E-value: 5.0e-79
Percent Identity: 43.2

References

No references are associated with this feature.