Pseudomonas putida HB3267, B479_21505

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas putida HB3267
GCF_000325725.1|latest
Locus Tag
B479_21505
Name
Replicon chromosome
Genomic location 4735115 - 4736317 (- strand)

Cross-References

RefSeq YP_007231133.1
GI 431804230
Entrez 14290681
INSDC AGA75190.1
NCBI Locus Tag B479_21505
UniParc UPI000217378D
UniProtKB Acc L0FRA9
UniProtKB ID L0FRA9_PSEPU
UniRef100 UniRef100_A0A099N574
UniRef50 UniRef50_P0C7L2
UniRef90 UniRef90_Q51956

Product

Feature Type CDS
Coding Frame 1
Product Name
beta-ketoadipyl CoA thiolase
Synonyms
Evidence for Translation
Charge (pH 7) -3.90
Kyte-Doolittle Hydrophobicity Value 0.045
Molecular Weight (kDa) 41.9
Isoelectric Point (pI) 5.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6PCB TRANSFERASE 06/17/19 Crystal structure of beta-ketoadipyl-CoA thiolase mutant (H356A) in complex with COA Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440) 1.61 X-RAY DIFFRACTION 96.8
6PCA TRANSFERASE 06/17/19 Crystal structure of beta-ketoadipyl-CoA thiolase Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440) 1.81 X-RAY DIFFRACTION 97.0
6PCC TRANSFERASE 06/17/19 Crystal structure of beta-ketoadipyl-CoA thiolase mutant (H356A) in complex hexanoyl coenzyme A Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440) 1.96 X-RAY DIFFRACTION 96.8
6PCD TRANSFERASE 06/17/19 Crystal structure of beta-ketoadipyl-CoA thiolase mutant (C90S-H356A) in complex Octanoyl coenzyme A Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440) 1.37 X-RAY DIFFRACTION 96.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 485 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000227 (529 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: B479_21505

Human Homologs

Ensembl 110, assembly GRCh38.p14
acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83]
E-value: 2.7e-80
Percent Identity: 43.2

References

No references are associated with this feature.