Pseudomonas aeruginosa UCBPP-PA14, PA14_00020 (dnaN)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_00020
Name
dnaN
Replicon chromosome
Genomic location 2056 - 3159 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14

Cross-References

RefSeq YP_788157.1
GI 116053722
EC Number 2.7.7.7
Entrez 4384100
INSDC ABJ14958.1
NCBI Locus Tag PA14_00020
UniParc UPI0000129706
UniProtKB Acc Q02V79
UniProtKB ID Q02V79_PSEAB
UniRef100 UniRef100_Q9I7C4
UniRef50 UniRef50_Q9I7C4
UniRef90 UniRef90_Q9I7C4

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA polymerase III subunit beta
Synonyms
Evidence for Translation
Charge (pH 7) -10.60
Kyte-Doolittle Hydrophobicity Value -0.147
Molecular Weight (kDa) 40.7
Isoelectric Point (pI) 4.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6AMS TRANSFERASE 08/11/17 Crystal structure of the DNA polymerase III subunit beta from Pseudomonas aeruginosa Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.39 X-RAY DIFFRACTION 100.0
4TSZ TRANSFERASE 06/19/14 Crystal structure of DNA polymerase sliding clamp from Pseudomonas aeruginosa with ligand Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT 2 X-RAY DIFFRACTION 100.0
4TR8 DNA BINDING PROTEIN 06/15/14 Crystal structure of DNA polymerase sliding clamp from Pseudomonas aeruginosa Pseudomonas aeruginosa HB15 1.8 X-RAY DIFFRACTION 100.0
6PTH TRANSFERASE/ANTIBIOTIC 07/15/19 Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Pseudomonas aeruginosa bound to griselimycin Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT 3.05 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 588 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000002 (538 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_00020
Search term: dnaN

Human Homologs

References

No references are associated with this feature.