Pseudomonas aeruginosa UCBPP-PA14, PA14_01960

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_01960
Name
Replicon chromosome
Genomic location 177315 - 178385 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq YP_788315.1
GI 116053878
Entrez 4383557
INSDC ABJ15114.1
NCBI Locus Tag PA14_01960
UniParc UPI00000C4F6C
UniProtKB Acc Q02US1
UniProtKB ID Q02US1_PSEAB
UniRef100 UniRef100_A0A077JP41
UniRef50 UniRef50_G8PZD9
UniRef90 UniRef90_W0YL24

Product

Feature Type CDS
Coding Frame 1
Product Name
RND efflux membrane fusion protein
Synonyms
Evidence for Translation
Charge (pH 7) 2.22
Kyte-Doolittle Hydrophobicity Value -0.241
Molecular Weight (kDa) 38.3
Isoelectric Point (pI) 9.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
TriB TriB is a membrane protein that is fused to TriA and both are required for the triclosan efflux pump function of TriABC-OpmH in P. aeruginosa. [PMID:17720796] ARO:3003680 protein homolog model Perfect 667.5 100.0 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6VEJ TRANSPORT PROTEIN 01/02/20 TriABC transporter from Pseudomonas aeruginosa Pseudomonas aeruginosa 4.5 ELECTRON MICROSCOPY 98.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 416 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000155 (490 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_01960

Human Homologs

References

No references are associated with this feature.