Pseudomonas aeruginosa UCBPP-PA14, PA14_01970

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_01970
Name
Replicon chromosome
Genomic location 178382 - 181429 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 8 transposon mutants in orthologs

Cross-References

RefSeq YP_788316.1
GI 116053879
Entrez 4383558
INSDC ABJ15115.1
NCBI Locus Tag PA14_01970
UniParc UPI0000396C69
UniProtKB Acc Q02US0
UniProtKB ID Q02US0_PSEAB
UniRef100 UniRef100_W1MWR2
UniRef50 UniRef50_F6A9K9
UniRef90 UniRef90_W0YJL0

Product

Feature Type CDS
Coding Frame 1
Product Name
RND efflux transporter
Synonyms
Evidence for Translation
Charge (pH 7) -8.33
Kyte-Doolittle Hydrophobicity Value 0.186
Molecular Weight (kDa) 111.9
Isoelectric Point (pI) 5.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
TriC TriC is a resistance nodulation cell division (RND) transporter that is a part of TriABC-OpmH, a triclosan-specific efflux protein. [PMID:17720796] ARO:3003681 protein homolog model Strict 1936.0 99.8 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6VEJ TRANSPORT PROTEIN 01/02/20 TriABC transporter from Pseudomonas aeruginosa Pseudomonas aeruginosa 4.5 ELECTRON MICROSCOPY 99.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000156 (999 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_01970

Human Homologs

References

No references are associated with this feature.