Pseudomonas aeruginosa UCBPP-PA14, PA14_46680

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_46680
Name
Replicon chromosome
Genomic location 4160669 - 4162102 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 8 transposon mutants in orthologs

Cross-References

RefSeq YP_791884.1
GI 116049313
Entrez 4382278
INSDC ABJ10549.1
NCBI Locus Tag PA14_46680
UniParc UPI000045D12F
UniProtKB Acc Q02JK2
UniProtKB ID Q02JK2_PSEAB
UniRef100 UniRef100_S0IXI0
UniRef50 UniRef50_Q9I3Y3
UniRef90 UniRef90_Q9I3Y3

Product

Feature Type CDS
Coding Frame 1
Product Name
transporter
Synonyms
Evidence for Translation
Charge (pH 7) 13.31
Kyte-Doolittle Hydrophobicity Value 0.642
Molecular Weight (kDa) 50.8
Isoelectric Point (pI) 10.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
PmpM PmpM is a multidrug efflux pump belonging to the MATE family of Pseudomonas aeruginosa. PmpM is an H+ drug antiporter and is the first reported case of an H+ coupled efflux pump in the MATE family. PmpM confers resistance to fluoroquinolones, fradiomycin, benzalkonium chloride, chlorhexidine gluconate, ethidium bromide, tetraphenylphosphonium chloride (TPPCl), and rhodamine 6G. [PMID:14679249] ARO:3004077 protein homolog model Strict 922.2 99.58 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 451 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001295 (965 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_46680
Search term: transporter

Human Homologs

References

No references are associated with this feature.