Pseudomonas aeruginosa UCBPP-PA14, PA14_48840

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
GCF_000014625.1|latest
Locus Tag
PA14_48840
Name
Replicon chromosome
Genomic location 4341250 - 4342014 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_792055.1
GI 116049143
Entrez 4380139
INSDC ABJ10379.1
NCBI Locus Tag PA14_48840
UniParc UPI0000033BA5
UniProtKB Acc Q02J31
UniProtKB ID Q02J31_PSEAB
UniRef100 UniRef100_Q9I4E3
UniRef50 UniRef50_Q9I4E3
UniRef90 UniRef90_Q9I4E3

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Synonyms
Evidence for Translation
Charge (pH 7) -6.46
Kyte-Doolittle Hydrophobicity Value -0.229
Molecular Weight (kDa) 28.5
Isoelectric Point (pI) 5.42

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1H70 HYDROLASE 06/30/01 DDAH FROM PSEUDOMONAS AERUGINOSA. C249S MUTANT COMPLEXED WITH CITRULLINE PSEUDOMONAS AERUGINOSA 1.8 X-RAY DIFFRACTION 99.6
3RHY HYDROLASE 04/12/11 Crystal structure of the dimethylarginine dimethylaminohydrolase adduct with 4-chloro-2-hydroxymethylpyridine PSEUDOMONAS AERUGINOSA 2.18 X-RAY DIFFRACTION 100.0
3BPB HYDROLASE 12/18/07 Crystal structure of the dimethylarginine dimethylaminohydrolase H162G adduct with S-methyl-L-thiocitrulline PSEUDOMONAS AERUGINOSA 2.81 X-RAY DIFFRACTION 99.6

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 96 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001153 (301 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_48840

Human Homologs

Ensembl 97, assembly GRCh38.p12
dimethylarginine dimethylaminohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:2715]
E-value: 1.6e-26
Percent Identity: 30.8

References

No references are associated with this feature.