Pseudomonas aeruginosa UCBPP-PA14, PA14_49300

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
GCF_000014625.1|latest
Locus Tag
PA14_49300
Name
Replicon chromosome
Genomic location 4379275 - 4381332 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_792097.1
GI 116049101
Entrez 4380117
INSDC ABJ10337.1
NCBI Locus Tag PA14_49300
UniParc UPI0000E44B55
UniProtKB Acc Q02IY9
UniProtKB ID Q02IY9_PSEAB
UniRef100 UniRef100_S0IWY1
UniRef50 UniRef50_Q8RNT4
UniRef90 UniRef90_Q8RNT4

Product

Feature Type CDS
Coding Frame 1
Product Name
lipoxygenase
Synonyms
Evidence for Translation
Charge (pH 7) -2.42
Kyte-Doolittle Hydrophobicity Value 0.033
Molecular Weight (kDa) 74.6
Isoelectric Point (pI) 6.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5LC8 OXIDOREDUCTASE 06/20/16 Crystal Structure of specific mutant from Pseudomonas aeruginosa Lipoxygenase at 1.8A resolution PSEUDOMONAS AERUGINOSA 1.8 X-RAY DIFFRACTION 99.4
4G33 OXIDOREDUCTASE 07/13/12 Crystal Structure of a Phospholipid-Lipoxygenase Complex from Pseudomonas aeruginosa at 2.0 A (C2221) PSEUDOMONAS AERUGINOSA 2.03 X-RAY DIFFRACTION 99.1
4G32 OXIDOREDUCTASE 07/13/12 Crystal Structure of a Phospholipid-Lipoxygenase Complex from Pseudomonas aeruginosa at 1.75A (P21212) PSEUDOMONAS AERUGINOSA 1.75 X-RAY DIFFRACTION 99.1
5IR4 OXIDOREDUCTASE 03/12/16 Crystal structure of wild-type bacterial lipoxygenase from Pseudomonas aeruginosa PA-LOX with space group C2221 at 1.48 A resolution PSEUDOMONAS AERUGINOSA 1.48 X-RAY DIFFRACTION 99.1
4RPE OXIDOREDUCTASE 10/30/14 Crystal Structure of Variant G186E from Pseudomonas Aeruginosa Lipoxygenase 2 at 1.60A (C2) PSEUDOMONAS AERUGINOSA 1.6 X-RAY DIFFRACTION 99.0
5IR5 OXIDOREDUCTASE 03/12/16 Crystal structure of wild-type bacterial lipoxygenase from Pseudomonas aeruginosa PA-LOX with space group P21212 at 1.9 A resolution PSEUDOMONAS AERUGINOSA 1.9 X-RAY DIFFRACTION 99.1

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 20 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001127 (301 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_49300
Search term: lipoxygenase

Human Homologs

Ensembl 97, assembly GRCh38.p12
arachidonate lipoxygenase 3 [Source:HGNC Symbol;Acc:HGNC:13743]
E-value: 2.2e-51
Percent Identity: 31.1

Human Homologs

Ensembl 97, assembly GRCh38.p12
arachidonate lipoxygenase 3 [Source:HGNC Symbol;Acc:HGNC:13743]
E-value: 2.2e-51
Percent Identity: 31.1

Human Homologs

Ensembl 97, assembly GRCh38.p12
arachidonate lipoxygenase 3 [Source:HGNC Symbol;Acc:HGNC:13743]
E-value: 2.2e-51
Percent Identity: 31.1

References

No references are associated with this feature.