Pseudomonas aeruginosa UCBPP-PA14, PA14_52260

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_52260
Name
Replicon chromosome
Genomic location 4635805 - 4638582 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14

Cross-References

RefSeq YP_792348.1
GI 116048851
Entrez 4383100
INSDC ABJ10087.1
NCBI Locus Tag PA14_52260
UniParc UPI00000D428B
UniProtKB Acc Q02I88
UniProtKB ID Q02I88_PSEAB
UniRef100 UniRef100_G3XD98
UniRef50 UniRef50_P48027
UniRef90 UniRef90_G3XD98

Product

Feature Type CDS
Coding Frame 1
Product Name
sensor/response regulator hybrid
Synonyms
Evidence for Translation
Charge (pH 7) -35.52
Kyte-Doolittle Hydrophobicity Value -0.160
Molecular Weight (kDa) 101.0
Isoelectric Point (pI) 4.71

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5O7J SIGNALING PROTEIN 06/09/17 Structural insights into the periplasmic sensor domain of the GacS histidine kinase controlling biofilm formation in Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA NOT SOLUTION NMR 100.0

Virulence Evidence

Source 1
Database PseudoCAP
Category
Evidence ECO:0000314
direct assay evidence used in manual assertion
Host Organism Danio rerio
Notes
Infection model Zebrafish embryo survival
Reference 21971182
Source 2
Database PseudoCAP
Category
Evidence ECO:0000015
mutant phenotype evidence
Host Organism Caenorhabditis elegans
Notes
Infection model C. elegans slow killing assay.
Reference 22911607

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 624 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000894 (544 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_52260

References

No references are associated with this feature.