Pseudomonas aeruginosa UCBPP-PA14, PA14_52670 (astD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
GCF_000014625.1|latest
Locus Tag
PA14_52670
Name
astD
Replicon chromosome
Genomic location 4668703 - 4670169 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq YP_792378.1
GI 116048822
Entrez 4385602
NCBI Locus Tag PA14_52670

Product

Feature Type CDS
Coding Frame 1
Product Name
succinylglutamic semialdehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -4.70
Kyte-Doolittle Hydrophobicity Value 0.081
Molecular Weight (kDa) 51.5
Isoelectric Point (pI) 6.19

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3JU8 OXIDOREDUCTASE 09/14/09 Crystal Structure of Succinylglutamic Semialdehyde Dehydrogenase from Pseudomonas aeruginosa. PSEUDOMONAS AERUGINOSA 1.82 X-RAY DIFFRACTION 99.0

Virulence Evidence

Source 1
Database PseudoCAP
Category
Evidence ECO:0000015
mutant phenotype evidence
Host Organism Caenorhabditis elegans
Notes
Infection model C. elegans slow killing assay.
Reference 22911607

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 599 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000865 (525 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_52670
Search term: astD

Human Homologs

Ensembl 97, assembly GRCh38.p12
aldehyde dehydrogenase 8 family member A1 [Source:HGNC Symbol;Acc:HGNC:15471]
E-value: 3.2e-44
Percent Identity: 29.8

References

No references are associated with this feature.