Pseudomonas aeruginosa UCBPP-PA14, PA14_67220 (tle5b)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_67220
Name
tle5b
Replicon chromosome
Genomic location 5999498 - 6001735 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_793559.1
GI 116053236
Entrez 4383401
INSDC ABJ14472.1
NCBI Locus Tag PA14_67220
UniParc UPI000045D50B
UniProtKB Acc Q02ES7
UniProtKB ID Q02ES7_PSEAB
UniRef100 UniRef100_Q02ES7
UniRef50 UniRef50_Q9HU94
UniRef90 UniRef90_Q9HU94

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion phospholipase D effector Tle5b
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -1.17
Kyte-Doolittle Hydrophobicity Value -0.588
Molecular Weight (kDa) 83.3
Isoelectric Point (pI) 6.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 66 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004687 (323 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_67220
Search term: tle5b

Human Homologs

References

RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A
Proc Natl Acad Sci U S A 2017 Jul 18;114(29):7707-7712
PubMed ID: 28673999