Pseudomonas aeruginosa PA7, PSPA7_0314 (pcaF)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PA7 GCF_000017205.1|latest
Locus Tag	PSPA7_0314
Name	pcaF
Replicon	chromosome
Genomic location	325555 - 326760 (+ strand)

Cross-References

RefSeq	YP_001345710.1
GI	152986310
EC Number	2.3.1.-
Entrez	5358343
INSDC	ABR83493.1
NCBI Locus Tag	PSPA7_0314
UniParc	UPI0000D73542
UniProtKB Acc	A6UY25
UniProtKB ID	A6UY25_PSEA7
UniRef100	UniRef100_A6UY25
UniRef50	UniRef50_P0C7L2
UniRef90	UniRef90_Q9I6R0

Product

Feature Type	CDS
Coding Frame	1
Product Name	beta-ketoadipyl CoA thiolase
Synonyms
Evidence for Translation
Charge (pH 7)	-2.93
Kyte-Doolittle Hydrophobicity Value	0.008
Molecular Weight (kDa)	42142.8
Isoelectric Point (pI)	6.08

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 474 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000227 (529 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPA7_0314 Search term: pcaF Search term: beta-ketoadipyl CoA thiolase

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000285093 acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83] E-value: 5.6e-78 Percent Identity: 42.1

References