Pseudomonas aeruginosa PA7, PSPA7_1601 (algE)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PA7 GCF_000017205.1|latest
Locus Tag	PSPA7_1601
Name	algE
Replicon	chromosome
Genomic location	1632765 - 1634237 (- strand)

Cross-References

RefSeq	YP_001346985.1
GI	152984949
Entrez	5355427
INSDC	ABR82132.1
NCBI Locus Tag	PSPA7_1601
UniParc	UPI0000D72ED4
UniProtKB Acc	A6V1Q0
UniProtKB ID	A6V1Q0_PSEA7
UniRef100	UniRef100_A6V1Q0
UniRef50	UniRef50_P18895
UniRef90	UniRef90_P18895

Product

Feature Type	CDS
Coding Frame	1
Product Name	alginate production outer membrane protein AlgE
Synonyms
Evidence for Translation
Charge (pH 7)	-20.33
Kyte-Doolittle Hydrophobicity Value	-0.637
Molecular Weight (kDa)	54.4
Isoelectric Point (pI)	4.67

Subcellular localization

Individual Mappings	Localization Confidence PMID Outer Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
3RBH	TRANSPORT PROTEIN	03/29/11	Structure of alginate export protein AlgE from Pseudomonas aeruginosa	Pseudomonas aeruginosa	2.301	X-RAY DIFFRACTION	99.3
4XNK	TRANSPORT PROTEIN	01/15/15	X-ray structure of AlgE1	Pseudomonas aeruginosa PAO1	2.8	X-RAY DIFFRACTION	99.4
4AFK	MEMBRANE PROTEIN	01/19/12	In meso structure of alginate transporter, AlgE, from Pseudomonas aeruginosa, PAO1	PSEUDOMONAS AERUGINOSA	1.897	X-RAY DIFFRACTION	99.3
5IYU	MEMBRANE PROTEIN	03/24/16	AlgE_CIM	Pseudomonas aeruginosa PAO1	2.7	X-RAY DIFFRACTION	99.4
4AZL	MEMBRANE PROTEIN	06/26/12	In meso structure of alginate transporter, AlgE, from Pseudomoas aeruginosa, PAO1, crystal form 2.	PSEUDOMONAS AERUGINOSA	2.8	X-RAY DIFFRACTION	99.3
4XNL	TRANSPORT PROTEIN	01/15/15	X-ray structure of AlgE2	Pseudomonas aeruginosa PAO1	2.9	X-RAY DIFFRACTION	99.4
7ACG	MEMBRANE PROTEIN	09/10/20	In meso structure of the alginate exporter, AlgE, from Pseudomonas aeruginosa in 9.8 monoacylglycerol	Pseudomonas aeruginosa	1.85	X-RAY DIFFRACTION	99.3
4B61	MEMBRANE PROTEIN	08/08/12	In meso structure of alginate transporter, AlgE, from Pseudomoas aeruginosa, PAO1. Crystal form 3.	PSEUDOMONAS AERUGINOSA PAO1	2.402	X-RAY DIFFRACTION	99.3
5D5D	TRANSPORT PROTEIN	08/10/15	In meso in situ serial X-ray crystallography structure of AlgE at 100 K	Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)	2.4	X-RAY DIFFRACTION	99.4

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 6 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002122 (490 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPA7_1601 Search term: algE Search term: alginate production outer membrane protein AlgE

Human Homologs

References