Pseudomonas aeruginosa PA7, PSPA7_4749 (rnc)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PA7 GCF_000017205.1|latest
Locus Tag	PSPA7_4749
Name	rnc
Replicon	chromosome
Genomic location	4882585 - 4883274 (- strand)

Cross-References

RefSeq	YP_001350091.1
GI	152986476
EC Number	3.1.26.3
Entrez	5359849
INSDC	ABR83659.1
NCBI Locus Tag	PSPA7_4749
UniParc	UPI0000D7257F
UniProtKB Acc	A6VAK6
UniProtKB ID	RNC_PSEA7
UniRef100	UniRef100_A6VAK6
UniRef50	UniRef50_B7UYX2
UniRef90	UniRef90_B7UYX2

Product

Feature Type	CDS
Coding Frame	1
Product Name	ribonuclease III
Synonyms
Evidence for Translation
Charge (pH 7)	-2.40
Kyte-Doolittle Hydrophobicity Value	-0.261
Molecular Weight (kDa)	25.5
Isoelectric Point (pI)	6.40

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 589 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000744 (535 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPA7_4749 Search term: rnc Search term: ribonuclease III

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000376783 dicer 1, ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17098] E-value: 3.6e-13 Percent Identity: 27.7
Ensembl 110, assembly GRCh38.p14	ENSP00000502730 dicer 1, ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17098] E-value: 3.6e-13 Percent Identity: 27.7
Ensembl 110, assembly GRCh38.p14	ENSP00000433926 dicer 1, ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17098] E-value: 3.6e-13 Percent Identity: 27.7
Ensembl 110, assembly GRCh38.p14	ENSP00000343745 dicer 1, ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17098] E-value: 3.6e-13 Percent Identity: 27.7
Ensembl 110, assembly GRCh38.p14	ENSP00000435681 dicer 1, ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17098] E-value: 3.6e-13 Percent Identity: 27.7
Ensembl 110, assembly GRCh38.p14	ENSP00000433060 dicer 1, ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17098] E-value: 3.6e-13 Percent Identity: 27.7
Ensembl 110, assembly GRCh38.p14	ENSP00000437256 dicer 1, ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17098] E-value: 3.6e-13 Percent Identity: 27.7

References