Pseudomonas aeruginosa PA7, PSPA7_6288 (dsbA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_6288
Name
dsbA
Replicon chromosome
Genomic location 6505133 - 6505768 (- strand)

Cross-References

RefSeq YP_001351599.1
GI 152989017
Entrez 5353543
NCBI Locus Tag PSPA7_6288

Product

Feature Type CDS
Coding Frame 1
Product Name
thiol:disulfide interchange protein DsbA
Synonyms
Evidence for Translation
Charge (pH 7) -2.38
Kyte-Doolittle Hydrophobicity Value -0.077
Molecular Weight (kDa) 23449.0
Isoelectric Point (pI) 6.40

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5DCH OXIDOREDUCTASE 08/24/15 Crystal structure of Pseudomonas aeruginosa DsbA E82I in complex with MIPS-0000851 (3-[(2-METHYLBENZYL)SULFANYL]-4H-1,2,4-TRIAZOL-4-AMINE) Pseudomonas aeruginosa 1.447 X-RAY DIFFRACTION 96.9
5TLQ OXIDOREDUCTASE 10/11/16 Model structure of the oxidized PaDsbA1 and 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine complex Pseudomonas aeruginosa NOT SOLUTION NMR 98.4
4ZL7 OXIDOREDUCTASE 05/01/15 Crystal structure of Pseudomonas aeruginosa DsbA E82I: Crystal I Pseudomonas aeruginosa 1.922 X-RAY DIFFRACTION 96.9
2MBT OXIDOREDUCTASE 08/03/13 NMR study of PaDsbA Pseudomonas aeruginosa NOT SOLUTION NMR 98.4
4ZL8 OXIDOREDUCTASE 05/01/15 Crystal structure of Pseudomonas aeruginosa DsbA E82I: Crystal II Pseudomonas aeruginosa 1.395 X-RAY DIFFRACTION 96.9
4ZL9 OXIDOREDUCTASE 05/01/15 Crystal structure of Pseudomonas aeruginosa DsbA E82I: Crystal III Pseudomonas aeruginosa 1.7 X-RAY DIFFRACTION 96.9
3H93 TRANSCRIPTION REGULATOR 04/29/09 Crystal Structure of Pseudomonas aeruginosa DsbA Pseudomonas aeruginosa PAO1 1.501 X-RAY DIFFRACTION 97.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 150 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005029 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_6288
Search term: dsbA

Human Homologs

References

No references are associated with this feature.