Pseudomonas aeruginosa M18, PAM18_0087 (hcp1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa M18
GCF_000226155.1|latest
Locus Tag
PAM18_0087
Name
hcp1
Replicon chromosome
Genomic location 101811 - 102287 (+ strand)

Cross-References

RefSeq YP_005972678.1
GI 386056156
Entrez 12564104
NCBI Locus Tag PAM18_0087

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Synonyms
Evidence for Translation
Charge (pH 7) 0.68
Kyte-Doolittle Hydrophobicity Value -0.453
Molecular Weight (kDa) 16998.1
Isoelectric Point (pI) 7.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1Y12 structural genomics, unknown function 11/16/04 Structure of a hemolysin-coregulated protein from Pseudomonas aeruginosa Pseudomonas aeruginosa PAO1 1.95 X-RAY DIFFRACTION 100.0
4KSR PROTEIN TRANSPORT 05/17/13 Crystal Structure of the Vibrio cholerae ATPase GspE Hexamer Pseudomonas aeruginosa; Vibrio cholerae O1 4.2 X-RAY DIFFRACTION 100.0
6AP1 TRANSPORT PROTEIN 08/16/17 Vps4p-Vta1p complex with peptide binding to the central pore of Vps4p Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); Saccharomyces cerevisiae (strain ATCC 204508 / S288c); SYNTHETIC CONSTRUCT 3.2 ELECTRON MICROSCOPY 99.4
4KSS PROTEIN TRANSPORT 05/17/13 Crystal Structure of Vibrio cholerae ATPase GspsE Hexamer Pseudomonas aeruginosa; Vibrio cholerae O1 7.58 X-RAY DIFFRACTION 100.0
7O42 MEMBRANE PROTEIN 04/04/21 TrwK/VirB4unbound trimer of dimers complex (with Hcp1) from the R388 type IV secretion system determined by cryo-EM. Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); Salmonella dublin 4.1 ELECTRON MICROSCOPY 98.1

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 72 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000084 (750 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAM18_0087
Search term: hcp1

Human Homologs

References

No references are associated with this feature.