Pseudomonas aeruginosa M18, PAM18_0207 (mdcE)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa M18
GCF_000226155.1|latest |
| Locus Tag |
PAM18_0207
|
| Name |
mdcE
|
| Replicon | chromosome |
| Genomic location | 232749 - 233555 (+ strand) |
Cross-References
| RefSeq | YP_005972798.1 |
| GI | 386056276 |
| Entrez | 12564224 |
| NCBI Locus Tag | PAM18_0207 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
malonate decarboxylase subunit gamma
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 0.17 |
| Kyte-Doolittle Hydrophobicity Value | 0.035 |
| Molecular Weight (kDa) | 28.5 |
| Isoelectric Point (pI) | 7.08 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 5VIT | TRANSFERASE | 04/17/17 | Crystal structure of a Pseudomonas malonate decarboxylase hetero-tetramer in complex with malonate | Pseudomonas aeruginosa; Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) | 2.203 | X-RAY DIFFRACTION | 99.6 |
| 5VIP | TRANSFERASE | 04/17/17 | Crystal structure of Pseudomonas malonate decarboxylase MdcD-MdcE hetero-dimer | Pseudomonas aeruginosa | 1.857 | X-RAY DIFFRACTION | 99.6 |
| 5VJ1 | TRANSFERASE | 04/18/17 | Crystal structure of a Pseudomonas malonate decarboxylase hetero-tetramer in complex with coenzyme A | Pseudomonas aeruginosa; Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) | 2.995 | X-RAY DIFFRACTION | 99.6 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 57 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000211 (478 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PAM18_0207
Search term: mdcE
Search term: malonate decarboxylase subunit gamma
|
Human Homologs
References
No references are associated with this feature.