Strain |
Pseudomonas aeruginosa M18
GCF_000226155.1|latest |
Locus Tag |
PAM18_2656
|
Name |
pvdQ
|
Replicon | chromosome |
Genomic location | 2954728 - 2957016 (+ strand) |
RefSeq | YP_005975241.1 |
GI | 386058719 |
Entrez | 12566706 |
NCBI Locus Tag | PAM18_2656 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
protein PvdQ
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | 0.50 |
Kyte-Doolittle Hydrophobicity Value | -0.347 |
Molecular Weight (kDa) | 84.0 |
Isoelectric Point (pI) | 7.10 |
Individual Mappings | |
Additional evidence for subcellular localization |
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
2WYB | HYDROLASE | 11/16/09 | The quorum quenching N-acyl homoserine lactone acylase PvdQ with a covalently bound dodecanoic acid | PSEUDOMONAS AERUGINOSA | 2.1 | X-RAY DIFFRACTION | 99.8 |
4BTH | HYDROLASE | 06/18/13 | The LeuA146Trp,PheB24Tyr Double Mutant of the Quorum Quenching N-acyl Homoserine Lactone Acylase PvdQ Has an Altered Substrate Specificity Towards Small Acyl Chains | PSEUDOMONAS AERUGINOSA | 1.9 | X-RAY DIFFRACTION | 99.6 |
4M1J | HYDROLASE | 08/02/13 | Crystal structure of Pseudomonas aeruginosa PvdQ in complex with a transition state analogue | Pseudomonas aeruginosa | 1.8 | X-RAY DIFFRACTION | 99.8 |
4K2F | HYDROLASE/HYDROLASE INHIBITOR | 04/09/13 | Structure of Pseudomonas aeruginosa PvdQ bound to BRD-A08522488 | Pseudomonas aeruginosa | 1.99 | X-RAY DIFFRACTION | 99.8 |
4WKT | HYDROLASE/HYDROLASE Inhibitor | 10/03/14 | n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ | Pseudomonas aeruginosa | 1.782 | X-RAY DIFFRACTION | 99.8 |
5UBL | HYDROLASE | 12/20/16 | A circularly permuted version of PvdQ (cpPvdQ) | Pseudomonas aeruginosa | 1.8 | X-RAY DIFFRACTION | 99.8 |
2WYE | HYDROLASE | 11/16/09 | The quorum quenching N-acyl homoserine lactone acylase PvdQ is an Ntn- Hydrolase with an unusual substrate-binding pocket | PSEUDOMONAS AERUGINOSA | 1.8 | X-RAY DIFFRACTION | 99.8 |
4WKU | HYDROLASE/HYDROLASE Inhibitor | 10/03/14 | n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ | Pseudomonas aeruginosa | 2 | X-RAY DIFFRACTION | 99.8 |
3SRA | HYDROLASE | 07/07/11 | Structure of Pseudomonas aerugionsa PvdQ covalently acylated with myristic acid from PVDIq | Pseudomonas aeruginosa PAO1 | 2.3 | X-RAY DIFFRACTION | 99.8 |
2WYC | HYDROLASE | 11/16/09 | The quorum quenching N-acyl homoserine lactone acylase PvdQ in complex with 3-oxo-lauric acid | PSEUDOMONAS AERUGINOSA | 1.9 | X-RAY DIFFRACTION | 99.8 |
3SRC | HYDROLASE/HYDROLASE INHIBITOR | 07/07/11 | Structure of Pseudomonas aeruginosa PvdQ bound to NS2028 | Pseudomonas aeruginosa | 2 | X-RAY DIFFRACTION | 99.8 |
4WKS | HYDROLASE/HYDROLASE INHIBITOR | 10/03/14 | n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ | Pseudomonas aeruginosa | 1.629 | X-RAY DIFFRACTION | 99.8 |
3L94 | HYDROLASE | 01/04/10 | Structure of PvdQ covalently acylated with myristate | Pseudomonas aeruginosa | 1.95 | X-RAY DIFFRACTION | 99.8 |
3L91 | HYDROLASE | 01/04/10 | Structure of Pseudomonas aerugionsa PvdQ bound to octanoate | Pseudomonas aeruginosa | 1.66 | X-RAY DIFFRACTION | 99.8 |
5UBK | HYDROLASE | 12/20/16 | Inactive S1A/N269D-cpPvdQ mutant in complex with the pyoverdine precursor PVDIq reveals a specific binding pocket for the D-Tyr of this substrate | Pseudomonas aeruginosa | 2.55 | X-RAY DIFFRACTION | 99.5 |
2WYD | HYDROLASE | 11/16/09 | The quorum quenching N-acyl homoserine lactone acylase PvdQ in complex with dodecanoic acid | PSEUDOMONAS AERUGINOSA | 1.901 | X-RAY DIFFRACTION | 99.8 |
3SRB | HYDROLASE/HYDROLASE INHIBITOR | 07/07/11 | Structure of Pseudomonas aeruginosa PvdQ bound to SMER28 | Pseudomonas aeruginosa | 1.8 | X-RAY DIFFRACTION | 99.8 |
4WKV | HYDROLASE/HYDROLASE Inhibitor | 10/03/14 | n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ | Pseudomonas aeruginosa | 2.1434 | X-RAY DIFFRACTION | 99.8 |
4K2G | HYDROLASE/HYDROLASE INHIBITOR | 04/09/13 | Structure of Pseudomonas aeruginosa PvdQ bound to BRD-A33442372 | Pseudomonas aeruginosa | 2.3 | X-RAY DIFFRACTION | 99.8 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 181 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003142 (466 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PAM18_2656
Search term: pvdQ
Search term: protein PvdQ
|