Pseudomonas aeruginosa M18, PAM18_4038 (dapA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa M18
GCF_000226155.1|latest
Locus Tag
PAM18_4038
Name
dapA
Replicon chromosome
Genomic location 4472983 - 4473846 (- strand)

Cross-References

RefSeq YP_005976621.1
GI 386060099
Entrez 12568093
NCBI Locus Tag PAM18_4038

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydrodipicolinate synthase
Synonyms
Evidence for Translation
Charge (pH 7) -2.44
Kyte-Doolittle Hydrophobicity Value 0.020
Molecular Weight (kDa) 30989.5
Isoelectric Point (pI) 6.40

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3NOE LYASE 06/25/10 Crystal Structure of Dihydrodipicolinate synthase from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.95 X-RAY DIFFRACTION 98.6
3QZE LYASE 03/05/11 Crystal Structure of DapA (PA1010) at 1.6 A resolution Pseudomonas aeruginosa 1.59 X-RAY DIFFRACTION 100.0
3S8H LYASE 05/28/11 Structure of dihydrodipicolinate synthase complexed with 3-Hydroxypropanoic acid(HPA)at 2.70 A resolution Pseudomonas aeruginosa 2.7 X-RAY DIFFRACTION 98.6
3PUO LYASE 12/06/10 Crystal structure of dihydrodipicolinate synthase from Pseudomonas aeruginosa(PsDHDPS)complexed with L-lysine at 2.65A resolution Pseudomonas aeruginosa 2.65 X-RAY DIFFRACTION 98.6
6P90 STRUCTURAL PROTEIN 06/08/19 Crystal structure of PaDHDPS2-H56Q mutant Pseudomonas aeruginosa 1.9 X-RAY DIFFRACTION 99.7
3PS7 LYASE 12/01/10 Biochemical studies and crystal structure determination of dihydrodipicolinate synthase from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.85 X-RAY DIFFRACTION 98.6

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 633 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000973 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAM18_4038
Search term: dapA

Human Homologs

References

No references are associated with this feature.