Pseudomonas aeruginosa DK2, PADK2_00920

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa DK2
GCF_000271365.1|latest
Locus Tag
PADK2_00920
Name
Replicon chromosome
Genomic location 207030 - 208640 (- strand)

Cross-References

RefSeq YP_006480181.1
GI 392981594
Entrez 13171481
NCBI Locus Tag PADK2_00920

Product

Feature Type CDS
Coding Frame 1
Product Name
arylsulfatase
Synonyms
Evidence for Translation
Charge (pH 7) -12.39
Kyte-Doolittle Hydrophobicity Value -0.382
Molecular Weight (kDa) 59961.2
Isoelectric Point (pI) 5.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4CXK HYDROLASE 04/07/14 G9 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa PSEUDOMONAS AERUGINOSA 1.86 X-RAY DIFFRACTION 97.8
1HDH HYDROLASE 11/16/00 Arylsulfatase from Pseudomonas aeruginosa Pseudomonas aeruginosa 1.3 X-RAY DIFFRACTION 99.4
4CXS HYDROLASE 04/08/14 G4 mutant of PAS, arylsulfatase from Pseudomonas aeruginosa, in complex with Phenylphosphonic acid PSEUDOMONAS AERUGINOSA 2.3 X-RAY DIFFRACTION 98.3
4CXU HYDROLASE 04/08/14 G4 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa, in complex with 3-Br-Phenolphenylphosphonate PSEUDOMONAS AERUGINOSA 2.03 X-RAY DIFFRACTION 98.3
5AJ9 HYDROLASE 02/20/15 G7 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa PSEUDOMONAS AERUGINOSA 2 X-RAY DIFFRACTION 98.1
4CYR HYDROLASE 04/14/14 G4 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa PSEUDOMONAS AERUGINOSA 1.72 X-RAY DIFFRACTION 98.3
4CYS HYDROLASE 04/14/14 G6 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa, in complex with Phenylphosphonic acid PSEUDOMONAS AERUGINOSA 1.88 X-RAY DIFFRACTION 98.3

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 241 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000181 (366 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PADK2_00920
Search term: arylsulfatase

Human Homologs

Ensembl 110, assembly GRCh38.p14
arylsulfatase B [Source:HGNC Symbol;Acc:HGNC:714]
E-value: 3.4e-30
Percent Identity: 29.9
Ensembl 110, assembly GRCh38.p14
arylsulfatase B [Source:HGNC Symbol;Acc:HGNC:714]
E-value: 3.4e-30
Percent Identity: 29.9
Ensembl 110, assembly GRCh38.p14
arylsulfatase B [Source:HGNC Symbol;Acc:HGNC:714]
E-value: 3.4e-30
Percent Identity: 29.9

References

No references are associated with this feature.