Pseudomonas aeruginosa RP73, M062_03170 (trpC)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa RP73
GCF_000414035.1|latest |
| Locus Tag |
M062_03170
|
| Name |
trpC
|
| Replicon | chromosome |
| Genomic location | 682435 - 683271 (+ strand) |
Cross-References
| RefSeq | YP_008131097.1 |
| GI | 514408216 |
| EC Number | 4.1.1.48 |
| Entrez | 15958377 |
| NCBI Locus Tag | M062_03170 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
indole-3-glycerol-phosphate synthase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -11.35 |
| Kyte-Doolittle Hydrophobicity Value | 0.087 |
| Molecular Weight (kDa) | 30.3 |
| Isoelectric Point (pI) | 4.64 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 6Y88 | LYASE | 03/03/20 | IGPS (Indole-3-glycerol phosphate synthase) from Pseudomonas aeruginosa in complex with substrate inhibitor rCdRP | Pseudomonas aeruginosa | 2.09983 | X-RAY DIFFRACTION | 99.3 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 584 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000631 (536 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: M062_03170
Search term: trpC
Search term: indole-3-glycerol-phosphate synthase
|
Human Homologs
References
No references are associated with this feature.